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31 Using a conventional double knockout mouse model for the Gstp1 and p2 genes, we show that GSTP1/P2 is required for the activation of signaling pathways involved in liver regeneration

Thus, it appears important to evaluate vitamin B 12 status, as well as kidney function, in older individuals with elevated homocysteine levels prior to initiating homocysteine-lowering therapy

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Under pathological conditions, such as oxidative stress (OxS), inflammation, and other adverse factors, PSCs can become activated [9, 10]